
Prepare
Degrease, standardise pH and prime the epidermis.
5-agent antioxidant depigmentation system built around Glutathione, which converts dark pigment to lighter forms for visible brightening from the first session. Formulated with GSH-5A Complex.

Glutathione · Glycolic Acid · Kojic Acid · Lactic Acid · Salicylic Acid
Penta-Brightening Architecture™
A rep replies in under 2 minutes, 9 am to 7 pm IST.
Not sure it fits your patient? Ask us ↗The GSH-5A Complex pairs this master antioxidant with Glycolic Acid for surface resurfacing, Kojic Acid to block pigment production, Lactic Acid for hydrating exfoliation, and Salicylic Acid for deep pore penetration and anti-inflammatory action.
Ideal for stubborn melasma and full-body brightening. ~24 sessions per 30ml jar.
Penta-Brightening Architecture™
Antioxidant-forward depigmentation system with glutathione as primary melanin reducer

Master antioxidant, converts eumelanin to pheomelanin.

And Lactic resurface

Blocks darkening

Glycolic and Lactic resurface

Lipophilic penetration, anti-inflammatory.
Synergistic exfoliation at multiple depths.
Glutathione, Glycolic Acid, Kojic Acid, Lactic Acid, Salicylic Acid, Liquorice Extract, Tea Tree Extract
Indications and suitability.


Build only what you need. Tick the essentials you already own to remove them from your enquiry.
Edit jar quantity ↑
Degrease, standardise pH and prime the epidermis.

Apply according to this product’s protocol and jar label.

Use the product-specific endpoint instructions below; neutralisation depends on the selected formulation.

Follow post-procedure care instructions.
Essentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.
4–6 sessions · 14-day intervals · 5–20 min clinician-controlled contact · neutralize fully at endpoint
Cleanse and prep skin thoroughly
Apply product as directed by protocol
Follow post-procedure care instructions
The practical details, before you order.
Estimated pH 1.8–2.6, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.
104 reviews of prodermic 590 · 104 from verified orders
104 reviews
Very mild shedding on day 4 with 590, but the texture refinement and follicular clearing were immediate. Thick gel matrix of 590 is easy to control with a fan brush—doesn't run into the inner canthi or nasolabial crease.
Thumbs up 👍 Good clinical results on stubborn melasma.
Epidermal melanin index dropped visibly on mexameter evaluation after the second pass of 590. Uniform endpoint with 590 and predictable timing. Neutralised cleanly with NEUT.01 with zero prolonged stinging.
590 in use for stubborn melasma since a few months. Endpoint reads clearly; behaviour is consistent jar to jar. Jar size is small for full-face work.
Did not expect to write a review but here we are. Love that every active is printed right there on the jar.
Tried 590 on a small series of stubborn melasma patients first. Shedding completes within the week in most patients.
From formulation to follow-up.
Prodermic Clinical Course
Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.
Start the module ↗Learn the technique
The clinical course module behind 590.
Most often ordered alongside 590.
435 ↗Medium-depth multi-agent depigmentation system designed for resistant melasma and deep PIH that superficial peels cannot address.
₹4,995MRP · all inclusive
555 ↗Amino acid-enhanced 5-agent depigmentation system designed for deep, stubborn pigmentation that has not responded to standard acid protocols.
₹4,995MRP · all inclusive
565 ↗Gentle quad-acid depigmentation system specifically formulated for sensitive, rosacea-prone, and reactive skin types that cannot tolerate aggressive peels.
₹4,995MRP · all inclusive
580 ↗Retinoic-acid combination peel for melasma, post-inflammatory hyperpigmentation and sun damage.
₹10,995MRP · all inclusive