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Degrease, standardise pH and prime the epidermis.
Medium-depth multi-agent depigmentation system designed for resistant melasma and deep PIH that superficial peels cannot address. Formulated with MTP⁹ Complex.

Mandelic Acid · TCA · Fenol · Vitamin C · Glycolic Acid · Salicylic Acid · Ferulic Acid · Phytic Acid · Retinol
Nomelan Deep Depigmentation™
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Not sure it fits your patient? Ask us ↗The MTP⁹ Complex combines Mandelic Acid for deep lipophilic penetration, TCA for controlled medium-depth coagulative necrosis, and Phenol for protein denaturation and deep restructuring. Glycolic + Salicylic provide dual AHA/BHA surface exfoliation, while Ferulic + Vitamin C deliver an antioxidant cascade. Phytic Acid chelates iron-mediated oxidation and Retinol accelerates epidermal turnover.
For experienced practitioners only. ~6-8 sessions per 30ml jar.
Nomelan Deep Depigmentation™
Medium-depth multi-agent depigmentation with Mandelic-TCA-Phenol triad for resistant melasma and deep PIH

Lipophilic penetration into sebaceous follicle for deep depigmentation.

Medium-depth coagulative necrosis and protein denaturation for deep restructuring.



Dual AHA/BHA exfoliation of stratum corneum.


Antioxidant cascade protecting against oxidative damage during peel.


Epidermal turnover acceleration for faster recovery.
Mandelic Acid, TCA, Fenol, Glycolic Acid, Salicylic Acid, Ferulic Acid, Phytic Acid, Retinol, Vitamin C
Indications and suitability.



Sun spots on the face, hands and décolletage.

Build only what you need. Tick the essentials you already own to remove them from your enquiry.
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Degrease, standardise pH and prime the epidermis.

Apply according to this product’s protocol and jar label.

Use the product-specific endpoint instructions below; neutralisation depends on the selected formulation.

Follow post-procedure care instructions.
Essentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.
2-3 sessions · 21-28 day intervals · self-neutralizing · significant peeling 3-7 days
Cleanse and prep skin with PREP.01
Apply Nomelan protocol as directed
Self-neutralizing — significant peeling expected 3-7 days
Apply REST.01 post-procedure
The practical details, before you order.
Estimated pH 1.3–1.9, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.
110 reviews of prodermic 435 · 110 from verified orders
110 reviews
Visible softening of textural irregularities and recalcitrant melasma cleared up noticeably by week 4 of using 435. Packaging of 435 is clean and dispensary-friendly. Good shelf stability once opened.
Ordered 435 from Bangladesh after a colleague in India recommended it. Patients here are used to lighter peels; this one gets a visible result without drama. Works the same on my patients here as the Indian doctors describe. Customs added about a week, so order ahead. Will reorder.
First time ordering from India; 435 was the reason. Comparable to the European brand I was paying three times as much for. Works the same on my patients here as the Indian doctors describe. Courier handled it well; nothing leaked. Worth the wait.
Using 435 for recalcitrant melasma since the start of the year... Peeling starts day 3-4, skin becomes clear by third sitting. Quality is like imported peel only. Got invoice also. Good product 👍
One of my Fitzpatrick IV patients had zero visible desquamation with 435, yet her recalcitrant melasma cleared visibly by week three. Patch tested 435 48 hours prior on Fitzpatrick V; zero irritant response, proceeded with the full protocol smoothly.
Treated a series of Fitzpatrick IV patients with 435 for recalcitrant recalcitrant melasma; pigment clearance was uniform without rebound. Uniform endpoint with 435 and predictable timing. Neutralised cleanly with NEUT.01 with zero prolonged stinging.
From formulation to follow-up.
Prodermic Clinical Course
Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.
Start the module ↗Learn the technique
The clinical course module behind 435.
Most often ordered alongside 435.
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