
Prepare
Degrease, standardise pH and prime the epidermis.
Amino acid-enhanced 5-agent depigmentation system designed for deep, stubborn pigmentation that has not responded to standard acid protocols. Formulated with ARG-5M Complex.

Arginine · Mandelic Acid · Kojic Acid · Lactic Acid · Glycolic Acid
Amino-Acid Corrective Architecture™
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Not sure it fits your patient? Ask us ↗The ARG-5M Complex uses Arginine to boost blood flow and active ingredient delivery, Mandelic Acid for even penetration across oily and dry zones, Kojic Acid to block pigment production, Lactic Acid for hydrating exfoliation, and Glycolic Acid for surface-level dead skin removal.
Targets deeper pigmentation in Fitzpatrick III-V skin. Self-neutralizing format. ~24 sessions per 30ml jar.
Amino-Acid Corrective Architecture™
Arginine-enhanced depigmentation system with mandelic acid for uniform lipophilic penetration

Nitric oxide precursor, enhances microcirculation.

Lipophilic AHA, slower penetration = less irritation.

Blocks pigment

And Glycolic resurface at different depths

Lactic and Glycolic resurface at different depths
Progressive exfoliation.
Arginine, Mandelic Acid, Kojic Acid, Lactic Acid, Glycolic Acid, Liquorice Extract, Tea Tree Extract
Indications and suitability.

Build only what you need. Tick the essentials you already own to remove them from your enquiry.
Edit jar quantity ↑
Degrease, standardise pH and prime the epidermis.

Apply according to this product’s protocol and jar label.

Use the product-specific endpoint instructions below; neutralisation depends on the selected formulation.

Follow post-procedure care instructions.
Essentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.
4–6 sessions · 14-day intervals · 5–15 min clinician-controlled contact · neutralize fully at endpoint
Cleanse and prep skin thoroughly
Apply product as directed by protocol
Follow post-procedure care instructions
The practical details, before you order.
Estimated pH 2.5–3.5, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.
100 reviews of prodermic 555 · 100 from verified orders
100 reviews
No aggressive peeling noticed on my mature deep pigmentation patient after 555, but her skin had a noticeable glow and the dullness was completely lifted. Clean endpoint reading with De-Pigmento makes training junior associate clinicians straightforward and safe.
Patients here are used to lighter peels; this one gets a visible result without drama. Customs added about a week, so order ahead. Shipping cost is the only real minus.
No aggressive peeling noticed on my mature deep pigmentation patient after 555, but her skin had a noticeable glow and the dullness was completely lifted. Patient found day-4 flaking from 555 slightly visible for office work; advise scheduling on Wednesday evening.
ok ok product. Results slow on deep pigmentation.
Results are very good for deep pigmentation, patients happy. Price little high.
Four stars because I want a bigger jar and nobody is listening. Patients see the change after the second session and come back without me chasing them.
From formulation to follow-up.
Prodermic Clinical Course
Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.
Start the module ↗Learn the technique
The clinical course module behind 555.
Most often ordered alongside 555.
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580 ↗Retinoic-acid combination peel for melasma, post-inflammatory hyperpigmentation and sun damage.
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590 ↗5-agent antioxidant depigmentation system built around Glutathione, which converts dark pigment to lighter forms for visible brightening from the first session.
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