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555: De-Pigmento Protocol De-Pigmento for Melasma & PIH

4.1100 reviews

Amino acid-enhanced 5-agent depigmentation system designed for deep, stubborn pigmentation that has not responded to standard acid protocols. Formulated with ARG-5M Complex.

₹4,995MRP per jar · all inclusive
1
Clinic pricing on WhatsApp ↗
Same-day dispatch for orders before 2 pm IST.
Fast shipping only · tracked.
Delivered pan-India in 2–4 days.

A rep replies in under 2 minutes, 9 am to 7 pm IST.

Not sure it fits your patient? Ask us ↗

What 555 does

The ARG-5M Complex uses Arginine to boost blood flow and active ingredient delivery, Mandelic Acid for even penetration across oily and dry zones, Kojic Acid to block pigment production, Lactic Acid for hydrating exfoliation, and Glycolic Acid for surface-level dead skin removal.

Targets deeper pigmentation in Fitzpatrick III-V skin. Self-neutralizing format. ~24 sessions per 30ml jar.

How it works

Amino-Acid Corrective Architecture™

Arginine-enhanced depigmentation system with mandelic acid for uniform lipophilic penetration

Arginine raw ingredient

Arginine

ARG-5M · amino acid

Nitric oxide precursor, enhances microcirculation.

Mandelic Acid raw ingredient

Mandelic Acid

ARG-5M · from bitter almond

Lipophilic AHA, slower penetration = less irritation.

Kojic Acid raw ingredient

Kojic Acid

ARG-5M · from koji fermentation

Blocks pigment

Lactic Acid raw ingredient

Lactic Acid

ARG-5M · from fermentation

And Glycolic resurface at different depths

Glycolic Acid raw ingredient

Glycolic Acid

ARG-5M · from sugar cane

Lactic and Glycolic resurface at different depths

Multi-acid

Progressive exfoliation.

Full ingredient list

Arginine, Mandelic Acid, Kojic Acid, Lactic Acid, Glycolic Acid, Liquorice Extract, Tea Tree Extract

Patient selection

Indications and suitability.

Deep Pigmentation

Fitzpatrick IV-VI
Stubborn Melasma

Not for

  • Active skin infections
  • Compromised skin barrier
  • Pregnancy (consult physician)

In the clinic. In your order.

Build only what you need. Tick the essentials you already own to remove them from your enquiry.

Edit jar quantity ↑
Prodermic PREP.01 Pre Protocol
01PREP.01

Prepare

Degrease, standardise pH and prime the epidermis.

₹348
MRP · all inclusive
Prodermic 555 De-Pigmento
02555

Apply the peel

Apply according to this product’s protocol and jar label.

₹4,995
MRP · all inclusive
1 jar in your enquiry
Prodermic NEUT.01 Neutralizer
03NEUT.01

Endpoint care

Use the product-specific endpoint instructions below; neutralisation depends on the selected formulation.

₹448
MRP · all inclusive
Prodermic REST.01 Recovery Balm
04REST.01

Recover

Follow post-procedure care instructions.

₹450
MRP · all inclusive
Selected stack · MRP · all inclusive₹6,241

1 jar + 3 clinical essentials

Clinic pricing on WhatsApp ↗

Essentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.

4–6 sessions · 14-day intervals · 5–15 min clinician-controlled contact · neutralize fully at endpoint

Application protocol

  1. 01

    Cleanse and prep skin thoroughly

  2. 02

    Apply product as directed by protocol

  3. 03

    Follow post-procedure care instructions

Frequency · As prescribed by professional

Specifications

The practical details, before you order.

Clinical profile

Peel depth
Medium-Deep
Fitzpatrick
III–V
Category
Combo Peel
Treatment
In-Clinic
Downtime
3-7 days
Use
As prescribed by professional

Inside the pack

Size
30ml
Yield
24 sessions
Shelf life
24 months

Ordering & delivery

Dispatch
Same dayOrders before 2 pm IST
Delivery
2–4 daysPan-India, tracked
Minimum order
1 unit
Price basis
MRP · all inclusiveClinic pricing on WhatsApp
Formulation reference: estimated pH

Estimated pH 2.5–3.5, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.

Clinician reviews

100 reviews of prodermic 555 · 100 from verified orders

100 reviews

All 100 reviews
  1. Dr. Rohan NarasimhanDermatologist · Mangaluru

    Clinic standard for deep pigmentation

    No aggressive peeling noticed on my mature deep pigmentation patient after 555, but her skin had a noticeable glow and the dullness was completely lifted. Clean endpoint reading with De-Pigmento makes training junior associate clinicians straightforward and safe.

    Verified orderReport
  2. Dr. Chong Li IsmailClinic Owner · Kuala Lumpur

    Plan for customs

    Patients here are used to lighter peels; this one gets a visible result without drama. Customs added about a week, so order ahead. Shipping cost is the only real minus.

    Verified orderReport
  3. Dr. Richa RajagopalClinic Owner · Visakhapatnam

    Clinical observation 555 sitting 65

    No aggressive peeling noticed on my mature deep pigmentation patient after 555, but her skin had a noticeable glow and the dullness was completely lifted. Patient found day-4 flaking from 555 slightly visible for office work; advise scheduling on Wednesday evening.

    Verified orderReport
  4. Dr. Vidya ChandranDermatologist · Indore

    ok ok product. Results slow on deep pigmentation.

    Verified orderReport
  5. Dr. Sanjay MishraDermatologist · Patna

    Good product

    Results are very good for deep pigmentation, patients happy. Price little high.

    Verified orderReport
  6. Dr. Arjun GillDermatologist · Madurai

    Four stars because I want a bigger jar and nobody is listening. Patients see the change after the second session and come back without me chasing them.

    Verified orderReport

Frequently asked questions

From formulation to follow-up.

How should I use 555?
Follow the application instructions in the protocol section above and the current product label. As prescribed by professional
How do I get clinic pricing?
₹4,995 is the MRP per pack, all inclusive. Clinic pricing and availability are confirmed on WhatsApp.

Prodermic Clinical Course

Know the protocol before the first patient.

Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.

Start the module ↗

Learn the technique

Pigmentation & Melasma

The clinical course module behind 555.

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