01 PreparePREP.01
Prepare
Degrease, standardise pH and prime the epidermis. Cleanse and prep skin thoroughly.
Before the peel
₹348
MRP · all inclusive580: Yellow Peel Protocol Yellow Peel (Retinoic Acid) for Melasma & PIH
4.8125 reviewsA retinol-led professional peel for melasma, post-inflammatory hyperpigmentation and sun damage. Its RGL-K⁴ Complex brings together Retinol, Glycolic Acid, Lactic Acid and Kojic Acid to combine skin renewal, controlled exfoliation and pigmentation care in one formulation.
Bestseller
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Jar size30 ml
Yield per jar18–22 sessions
UseProfessional use only
RGL-K⁴ ComplexFormulation system
Retinol · Glycolic Acid · Lactic Acid · Kojic Acid
RGL-K⁴ Complex brings these four actives together in one retinol-led formulation for professional pigmentation care.
₹10,995MRP per jar · all inclusive
580 jar quantity
Same-day dispatch for orders before 2 pm IST.
Fast shipping only · tracked.
Delivered pan-India in 2–4 days.
A rep replies in under 2 minutes, 9 am to 7 pm IST.
Not sure it fits your patient? Ask us ↗
Documented clinical case
One patient.
A course of care.
Mehak, 43 · Delhi
Bilateral melasma. Visible clearance across a 4-session course over 15 weeks.
4sessions
35days apart
15weeks
The photographs document visible change in the malar pigmentation over the course. They show an individual outcome, not a prediction for every patient.
During the protocol
Shedding photographs for patient counselling. These are not final outcomes.
In-clinic professional use · consent on file · individual results vary. Monochrome display; select a photograph to view the original in colour for clinical assessment.
What 580 does
Four named actives.
The RGL-K⁴ Complex.
Prodermic 580 is a professional depigmentation system designed for melasma, post-inflammatory hyperpigmentation (PIH), and sun damage spots. Its RGL-K⁴ Complex combines Retinol to speed up skin renewal, Glycolic Acid for controlled exfoliation, Lactic Acid for gentle hydrating peel action, and Kojic Acid to block pigment production. Requires neutralisation with NEUT.01 or cold water according to the current protocol. Each 30 ml jar yields 18–22 sessions.
How it works
Retinoid-driven epidermal turnover, alongside controlled exfoliation and pigment inhibition.
Retinol
Vitamin AAccelerates epidermal turnover, disperses melanin and inhibits tyrosinase.
Glycolic Acid
From sugar caneWorks with Lactic Acid to disrupt corneocyte cohesion for controlled desquamation.
Lactic Acid
From fermentationGentle hydrating peel action alongside Glycolic Acid’s controlled exfoliation.
Kojic Acid
From koji fermentationChelates the copper required for tyrosinase activity, targeting pigment production.
Full ingredient list
Retinol, Glycolic Acid, Lactic Acid, Kojic Acid, DM Water, Emulsifying Wax, Liquid Paraffin, Sodium EDTA, Methyl Paraben, Propyl Paraben, Cetyl Alcohol, Propylene Glycol, Xanthan Gum, Perfume
Patient selection
Indications and suitability before the first session.
Melasma
Epidermal and mixed-depth melasma, including long-standing malar patches.
PIH
Post-inflammatory hyperpigmentation after acne, procedures or friction.
Solar Lentigines
Sun spots on the face, hands and décolletage.
Photoaging
Uneven tone and dullness from cumulative sun exposure.
Fitzpatrick III–V with priming.
Not for
- Active skin infections
- Compromised skin barrier
- Pregnancy (consult physician)
In the clinic. In your order.
Prep, peel, neutralise, recover. The complete protocol stack, in the order it touches the skin.
Build only what you need. Tick the essentials you already own to remove them from your enquiry. Your 580 jar quantity follows the selector above.
Edit jar quantity ↑02 Apply580
Apply the peel
Use the jar-label contact time: 3–30 min, clinician-controlled. Monitor continuously; use the clinical endpoint.
As printed on the jar label
₹10,995
MRP · all inclusive1 jar in your enquiry
03 NeutraliseNEUT.01
Neutralise
Immediate pH restoration and real-time endpoint control. Neutralise at the endpoint, or earlier if an adverse response develops.
At the endpoint
₹448
MRP · all inclusive
04 RecoverREST.01
Recover
Barrier repair; faster re-epithelialisation and less downtime. Follow post-procedure care instructions.
Send home with it
₹450
MRP · all inclusiveEssentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.
Specifications
The practical details, before you order.
- Contact time
- 3–30 min · clinician-controlledAs printed on the jar label. Monitor the live skin response.
- Neutralise
- With NEUT.01Or cold water according to the current protocol.
- Course
- 4–6 sessions · one every 35 days
- Fitzpatrick
- III–V with priming
Clinical profile
- Peel depth
- Medium–Deep
- Fitzpatrick
- III–V with priming
- Category
- Combo Peel
- Treatment
- In-clinic
- Visible downtime
- 3–7 days
Inside the jar
- Size
- 30 ml
- Yield
- 18–22 sessions
- Contact time
- 3–30 minClinician-controlled, as printed on the jar label
- Shelf life
- 24 months
- Course
- 4–6 sessionsOne every 35 days
Ordering & delivery
- Dispatch
- Same dayOrders before 2 pm IST
- Delivery
- 2–4 daysPan-India, tracked
- Minimum order
- 1 unit
- Price basis
- MRP · all inclusiveClinic pricing on WhatsApp
Formulation reference: estimated pH
Estimated pH 1.6–2.4, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.
Clinician reviews
125 reviews of prodermic 580 · 125 from verified orders
125 reviews
- Dr. Anh GuhaDermatologist · Patna
Steady pigment clearance
Not every patient went through aggressive peeling with 580, but the dermal tone lightening and overall radiance after sitting two were remarkable. Patch tested 580 48 hours prior on Fitzpatrick V; zero irritant response, proceeded with the full protocol smoothly.
- Dr. Meghana RaoDermatologist
Moved 11 melasma patients from my imported yellow peel. No regrets.
Same day-4 to day-5 sheet shedding I was getting before, at about a third of the landed cost. Visible lightening by session 3 on all of them. I counted 19 sessions from the jar doing full face. GST invoice was in the box, which my CA needed.
- Dr. Anurag ManiDermatologist · Chennai
Zero downtime complaints
The lack of heavy peeling from 580 was actually a relief for my working patients who couldn't take leave. Packaging of 580 is clean and dispensary-friendly. Good shelf stability once opened.
- Dr. Sangeeta SarkarAesthetician · Manila
Clinical observation 580 sitting 72
Epidermal melanin index dropped visibly on mexameter evaluation after the second pass of 580. Packaging of 580 is clean and dispensary-friendly. Good shelf stability once opened.
- Dr. Shailesh MukhopadhyayCosmetologist · Vadodara
Reordered for clinic trolley
Reassured the patient that deep cell turnover doesn't always mean sheet flaking; 580 delivered excellent pigment clearance by day 25. Jar of 580 yields a solid 18–22 sessions when applied precisely with a fan brush. Excellent cost-to-outcome ratio.
- Dr. Imran SiddiquiDermatologist
Counsel with the day-5 photos and compliance goes up
I show every patient the mid-protocol photos from this page before session one. Nobody panics on day 4 anymore. The cream is thick enough to see where I have applied, and the endpoint is easy to call. First order was COD, now I prepay.
Frequently asked questions
From formulation to follow-up.
Is the Prodermic 580 Yellow Peel used for melasma?
Yes. The 580 Yellow Peel is a professional depigmentation peel formulated for melasma, post-inflammatory hyperpigmentation (PIH), and solar lentigines. Its Retinol + Kojic Acid pairing targets pigment while Glycolic and Lactic acids drive controlled exfoliation of pigmented layers. It is intended for in-clinic use by trained practitioners as part of a wider melasma protocol that includes strict photoprotection.
Is the Yellow Peel a retinoic acid peel?
It is a Retinol-led yellow peel, not a prescription retinoic acid (tretinoin) peel. It contains Retinol alongside Glycolic, Lactic and Kojic acids. The skin converts Retinol toward its active form.
How does it treat hyperpigmentation and PIH?
Through complementary pathways: Retinol accelerates epidermal turnover and disperses melanin; Kojic Acid chelates the copper required for tyrosinase, the pigment-forming enzyme; and Glycolic + Lactic acids exfoliate the outer pigmented layers. The system addresses pigment production and clearance.
Which Fitzpatrick types is the protocol intended for?
Fitzpatrick III–V with priming. It must be applied by a trained clinician with appropriate patient selection, conservative first sessions and rigorous sun protection. Skin of colour carries a higher PIH risk; assess the barrier and treatment history before selecting the protocol.
How many sessions per jar and how much downtime?
Each 30 ml jar yields 18–22 sessions. Typical visible downtime is 3–7 days of flaking and peeling, depending on the skin and protocol. Neutralise with NEUT.01 or cold water according to the current protocol.
What is the contact time and course interval?
Contact time is as printed on the jar label: 3–30 min, clinician-controlled. Assess Fitzpatrick type, barrier integrity, treatment history and live skin response. Monitor continuously and neutralise at the clinical endpoint, or earlier if an adverse response develops. A course is 4–6 sessions, one every 35 days.
Is ₹10,995 the clinic price?
₹10,995 is the MRP per 30 ml jar, all inclusive. Clinic pricing is available only on WhatsApp. Use “Clinic pricing on WhatsApp” to enquire with your selected jar quantity or protocol stack.
When will my order arrive?
Same-day dispatch for orders before 2 pm IST. Delivery takes 2–4 days pan-India and is tracked. Cash on delivery is available. We use fast shipping only; overseas transit and customs timings vary.
Prodermic Clinical Course
Know the protocol before the first patient.
Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.
Start the moduleLearn the technique
Pigmentation & Melasma
The clinical course module behind 580. Patient selection, application, endpoint control and post-procedure care.
Also in Pigmentation & Melasma
Most often ordered alongside 580.
435 ↗Nomelan Protocol
Medium-depth multi-agent depigmentation system designed for resistant melasma and deep PIH that superficial peels cannot address.
₹4,995MRP · all inclusive
555 ↗De-Pigmento
Amino acid-enhanced 5-agent depigmentation system designed for deep, stubborn pigmentation that has not responded to standard acid protocols.
₹4,995MRP · all inclusive
565 ↗Melasmonil Peel
Gentle quad-acid depigmentation system specifically formulated for sensitive, rosacea-prone, and reactive skin types that cannot tolerate aggressive peels.
₹4,995MRP · all inclusive
590 ↗Glutathione Peel
5-agent antioxidant depigmentation system built around Glutathione, which converts dark pigment to lighter forms for visible brightening from the first session.
₹4,995MRP · all inclusive