
Prepare
Degrease, standardise pH and prime the epidermis.
Tri-acid acne system specifically designed for safe and effective acne treatment in Fitzpatrick IV-VI skin types, where standard peels carry elevated risk of post-acne dark spots. Formulated with MSA-3L Complex.

Mandelic Acid · Salicylic Acid · Glycolic Acid
Lipophilic Tri-Acid Acne System™
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Not sure it fits your patient? Ask us ↗The MSA-3L Complex uses Mandelic Acid for its larger molecular size enabling slower, more uniform penetration that avoids patchy results, Salicylic Acid for deep pore penetration and pore-clearing, and Glycolic Acid for controlled surface exfoliation.
The safest acne peel combination for darker skin types. Self-neutralizing format. ~24 sessions per 30ml jar.
Lipophilic Tri-Acid Acne System™
Mandelic-forward acne system specifically designed for safe use in Fitzpatrick IV–V

Larger molecular weight = slower penetration, less irritation. Safe for Fitzpatrick IV-VI.

Clears pores from within

Speeds surface renewal — the safest acne combo for darker skin
Balances efficacy with tolerability.
Mandelic Acid, Salicylic Acid, Glycolic Acid
Indications and suitability.


Skin that reacts, stings or flushes easily.
Build only what you need. Tick the essentials you already own to remove them from your enquiry.
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Degrease, standardise pH and prime the epidermis.

Apply according to this product’s protocol and jar label.

Use the product-specific endpoint instructions below; neutralisation depends on the selected formulation.

Follow post-procedure care instructions.
Essentials are one unit each. Clinic pricing and availability are confirmed on WhatsApp before you order.
4–6 sessions · 14-day intervals · 5–15 min clinician-controlled contact · neutralize fully at endpoint
Cleanse and prep skin thoroughly
Apply product as directed by protocol
Follow post-procedure care instructions
The practical details, before you order.
Estimated pH 1.9–2.7, with medium confidence, inferred from acid pKa and buffering. This is not a batch measurement and must not be used as a batch specification.
123 reviews of prodermic 475 · 123 from verified orders
123 reviews
No aggressive peeling noticed on my mature fitzpatrick iv-vi acne patient after 475, but her skin had a noticeable glow and the dullness was completely lifted. Clean endpoint reading with Mandelic Acnil makes training junior associate clinicians straightforward and safe.
Controlled epidermal exfoliation without harsh peeling sheets. 475 cleared recalcitrant fitzpatrick iv-vi acne steadily over 3 sessions. Results with 475 on fitzpatrick iv-vi acne are genuine, but patient counselling on post-procedure care is essential.
Protocol: PREP, 475, NEUT, REST, five-week spacing. Fitzpatrick IV and V tolerated it with PREP before and NEUT after. Repeatable result across three operators in our clinic. Dispatch same day; GST invoice enclosed.
Repeat order placed. Works well. Good on Fitzpatrick IV.
frost is even, application is easy.
Very mild shedding on day 4 with 475, but the texture refinement and follicular clearing were immediate. Solid 4 stars. Took three sittings with 475 to clear persistent pigment on cheekbones.
From formulation to follow-up.
Prodermic Clinical Course
Free, self-paced, written for practising dermatologists. The rationale behind every line on the label.
Start the module ↗Learn the technique
The clinical course module behind 475.
Most often ordered alongside 475.
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545 ↗6-agent hybrid protocol that simultaneously treats active acne and post-acne dark marks, eliminating the need for sequential treatment plans.
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