Overview
Step-by-step clinical application guide for practitioners
Safety
Contraindications
- Aspirin (salicylate) allergy
- Oral isotretinoin within the last 6 months
- Pregnancy or breastfeeding
- Active dermatitis, eczema or active skin infection in the treatment area
- Inflamed nodulocystic acne or open lesions in the treatment area
- Topical retinoids within 72 hours
- History of keloid or hypertrophic scarring
- Recent laser or IPL treatment within 2 weeks
- Active herpes simplex in the treatment area
Neutralize Immediately If
- Severe burning or escalating pain
- Excessive, deep-red erythema
- Visible edema or swelling
- Urticaria (hives or welts)
- Signs of salicylate sensitivity or allergic reaction
- Patient distress or inability to tolerate
Stop the procedure and neutralize with cold water or sodium bicarbonate.
Composition
| Ingredient | Concentration | Role |
|---|---|---|
| Salicylic Acid | Lipophilic BHA — dissolves into oily follicles, clears comedones and drives an even pseudo-frost peel | |
| Mandelic Acid | Large-molecule AHA — slow, uniform penetration with low PIH risk in darker phototypes; antibacterial | |
| Azelaic Acid | Inhibits tyrosinase and calms acne inflammation — treats pigment and acne together | |
| Tranexamic Acid | Interrupts the plasmin pathway that re-triggers melasma; fades red post-acne marks | |
| Phytic Acid | Chelating brightener with gentle, even exfoliation | |
| Zinc PCA + Kaolin | Sebum control in a grey clay base that mattifies and stays exactly where it is painted |
Indications
- Melasma on Oily Skin
- Post-Acne Marks (PIH)
- Open Pores
- Oily, Congested Skin
- Comedonal Acne
- Uneven Skin Tone
Procedure
- 01
Cleanse & Degrease
2–3 minCleanse with a gentle non-residue cleanser. Remove makeup, sunscreen and surface oil. Degrease thoroughly with PREP.01 on gauze — oily skin needs a complete degrease for an even peel.
- Degreasing contact: 1–2 minutes. Wipe clean and allow the skin to dry for 30 seconds.
- 02
Patch Test
10 minApply a small amount behind the ear or on the inner forearm. Observe for 10 minutes for any adverse reaction. Confirm there is no aspirin (salicylate) allergy.
- First session only. If erythema, itching or swelling occurs, do not proceed.
- 03
Apply prodermic 680
3–5 min, response-ledUsing a fan brush, apply an even layer of the grey clay cream: forehead, cheeks, nose, chin, upper lip. Avoid eyelids, lips and broken skin. The grey base shows coverage clearly, so no area is missed or doubled.
- Work systematically with uniform strokes. Keep a thin, even film.
- 04
Monitor & Titrate
3–5 minObserve continuously. Endpoint: an even white salicylic pseudo-frost with uniform erythema. Mild stinging is expected. This pseudo-frost is not a TCA frost — it rinses away.
- Session 1: stop at 3 minutes. Increase progressively to a 5-minute maximum. The observed endpoint always overrides the timer.
- 05
Neutralize
2–3 minApply NEUT.01 generously over the treated area at the endpoint, then remove all product and clay with cool water and damp gauze.
- Neutralize thoroughly. No residual clay or acid should remain on the skin.
- 06
Post-Peel Soothing & Discharge
3–5 minApply REST.01 recovery balm and SPF 50+ sunscreen. Give written post-care instructions and schedule the next session.
- Patient avoids sun, actives and makeup for the rest of the day.
Post-procedure
| Day 0 | Peel Day REST.01 applied. No actives or makeup for the rest of the day. Clean pillowcase. |
| Days 1–2 | Tightness Phase Skin feels tight and dry. Gentle cleanser twice daily, REST.01 3–4 times, SPF 50+. |
| Days 2–5 | Peeling Phase Visible flaking. Do NOT pick or force peeling. Continue REST.01 and SPF 50+. |
| Days 5–7 | Recovery Peeling complete. Light makeup can resume. Avoid harsh actives until Day 7. |
| Days 7–35 | Between Sessions Strict sun protection. Oil-balancing home care (ACN.sr or NVC.sr). Next session at 35 days. |
Session plan
| Session | Contact time |
|---|---|
| Session 1 | 3 min |
| Session 2 | 3–4 min |
| Session 3 | 4–5 min |
| Session 4+ | 5 min (max) |
