Overview
Step-by-step clinical application guide for practitioners
Safety
Contraindications
- Active dermatitis, eczema, or active skin infection in treatment area
- Pregnancy or breastfeeding
- Isotretinoin use within the last 6 months
- Topical tretinoin use within 72 hours
- Open wounds or broken skin in treatment area
- History of keloid or hypertrophic scarring
- Known allergy to any component
- Recent laser or IPL treatment within 2 weeks
- Active herpes simplex in treatment area
Neutralize Immediately If
- Severe burning or pain (escalating)
- Excessive/intense erythema (deep red)
- Visible edema or swelling
- Urticaria (hives or welts)
- Patient distress or inability to tolerate
- Signs of allergic reaction
Stop the procedure and neutralize with cold water or sodium bicarbonate.
Composition
| Ingredient | Concentration | Role |
|---|---|---|
| Retinol | Accelerates epidermal turnover, disperses melanin, inhibits tyrosinase activity | |
| Glycolic Acid | Disrupts corneocyte cohesion, enables controlled desquamation of pigmented layers | |
| Lactic Acid | Gentle exfoliation with built-in hydration, supports even penetration | |
| Kojic Acid | Chelates copper required for tyrosinase activity, blocking melanin synthesis |
Indications
- Melasma
- Post-Inflammatory Hyperpigmentation
- Solar Lentigines
- Photoaging
- Blotchy Pigmentation
- Uneven Skin Tone
Procedure
- 01
Cleanse & Degrease
2–3 minCleanse with gentle non-residue cleanser. Remove makeup, sunscreen, surface impurities. Degrease skin using pre-peel degreasing solution with gauze.
- Degreasing contact: 1–2 minutes. Wipe clean. Allow skin to dry for 30 seconds.
- 02
Patch Test
10 minApply a small amount behind the ear or on the inner forearm. Observe for 10 minutes for any adverse reaction.
- First session only. If erythema, itching, or swelling occurs, do not proceed.
- 03
Apply prodermic 580
3–5 minUsing a fan brush, apply 3–4g of product in a thin, even layer. Work systematically: forehead, cheeks, nose, chin, upper lip. Avoid eyelids and lips.
- Ensure uniform coverage. Use systematic strokes for even distribution.
- 04
Monitor & Titrate
10–30 minObserve the skin response continuously. Endpoints: mild uniform erythema (pink), slight stinging is normal. Watch for frosting or excessive redness.
- Session 1: target 10–15 min. Increase progressively in subsequent sessions up to 30 min maximum.
- 05
Neutralize
2–3 minApply sodium bicarbonate solution or cold water to neutralize the peel. Gently wipe with damp gauze until all product is removed.
- Neutralize thoroughly. Ensure no residual product remains on the skin.
- 06
Post-Peel Soothing & Discharge
3–5 minApply recovery moisturizer and SPF 50+ sunscreen. Provide written post-care instructions. Schedule follow-up.
- Patient should avoid sun exposure, actives, and makeup for remainder of day.
Post-procedure
| Day 0 | Peel Day Recovery moisturizer applied. No actives/makeup rest of day. Clean pillowcase. |
| Days 1–2 | Tightness Phase Skin tight, dry, possibly darkened. Gentle cleanser 2x daily. Thick moisturizer 3–4x. SPF 50+. |
| Days 3–5 | Peeling Phase Visible flaking begins. Do NOT force peeling. Continue moisturizer + SPF 50+. |
| Days 5–7 | Recovery Peeling mostly complete. Resume light makeup. Avoid harsh actives until Day 7. |
| Days 7–25 | Between Sessions Strict sun protection. Resume normal skincare. Next session in 25 days. |
Session plan
| Session | Contact time |
|---|---|
| Session 1 | 10–15 min |
| Session 2 | 15–20 min |
| Session 3 | 20–25 min |
| Session 4+ | 25–30 min (max) |
Expected results
Clinical outcomes from supervised sessions. Actual results depend on skin type, adherence to protocol, and sun protection.
