Yellow Peel

580

Step-by-step clinical application guide for practitioners

Depth
Superficial to Medium
Contact
10–30 min
Neutralize
Requires neutralization
Fitzpatrick
III–V
Sessions
4–6
Downtime
3–7 days

Overview

Step-by-step clinical application guide for practitioners

01

Safety

Contraindications

  • Active dermatitis, eczema, or active skin infection in treatment area
  • Pregnancy or breastfeeding
  • Isotretinoin use within the last 6 months
  • Topical tretinoin use within 72 hours
  • Open wounds or broken skin in treatment area
  • History of keloid or hypertrophic scarring
  • Known allergy to any component
  • Recent laser or IPL treatment within 2 weeks
  • Active herpes simplex in treatment area

Neutralize Immediately If

  1. Severe burning or pain (escalating)
  2. Excessive/intense erythema (deep red)
  3. Visible edema or swelling
  4. Urticaria (hives or welts)
  5. Patient distress or inability to tolerate
  6. Signs of allergic reaction

Stop the procedure and neutralize with cold water or sodium bicarbonate.

02

Composition

IngredientConcentrationRole
RetinolAccelerates epidermal turnover, disperses melanin, inhibits tyrosinase activity
Glycolic AcidDisrupts corneocyte cohesion, enables controlled desquamation of pigmented layers
Lactic AcidGentle exfoliation with built-in hydration, supports even penetration
Kojic AcidChelates copper required for tyrosinase activity, blocking melanin synthesis
03

Indications

Fitzpatrick III–V
  • Melasma
  • Post-Inflammatory Hyperpigmentation
  • Solar Lentigines
  • Photoaging
  • Blotchy Pigmentation
  • Uneven Skin Tone
04

Procedure

  1. 01

    Cleanse & Degrease

    2–3 min

    Cleanse with gentle non-residue cleanser. Remove makeup, sunscreen, surface impurities. Degrease skin using pre-peel degreasing solution with gauze.

    • Degreasing contact: 1–2 minutes. Wipe clean. Allow skin to dry for 30 seconds.
  2. 02

    Patch Test

    10 min

    Apply a small amount behind the ear or on the inner forearm. Observe for 10 minutes for any adverse reaction.

    • First session only. If erythema, itching, or swelling occurs, do not proceed.
  3. 03

    Apply prodermic 580

    3–5 min

    Using a fan brush, apply 3–4g of product in a thin, even layer. Work systematically: forehead, cheeks, nose, chin, upper lip. Avoid eyelids and lips.

    • Ensure uniform coverage. Use systematic strokes for even distribution.
  4. 04

    Monitor & Titrate

    10–30 min

    Observe the skin response continuously. Endpoints: mild uniform erythema (pink), slight stinging is normal. Watch for frosting or excessive redness.

    • Session 1: target 10–15 min. Increase progressively in subsequent sessions up to 30 min maximum.
  5. 05

    Neutralize

    2–3 min

    Apply sodium bicarbonate solution or cold water to neutralize the peel. Gently wipe with damp gauze until all product is removed.

    • Neutralize thoroughly. Ensure no residual product remains on the skin.
  6. 06

    Post-Peel Soothing & Discharge

    3–5 min

    Apply recovery moisturizer and SPF 50+ sunscreen. Provide written post-care instructions. Schedule follow-up.

    • Patient should avoid sun exposure, actives, and makeup for remainder of day.
05

Post-procedure

Daily regimen
Day 0Peel Day Recovery moisturizer applied. No actives/makeup rest of day. Clean pillowcase.
Days 1–2Tightness Phase Skin tight, dry, possibly darkened. Gentle cleanser 2x daily. Thick moisturizer 3–4x. SPF 50+.
Days 3–5Peeling Phase Visible flaking begins. Do NOT force peeling. Continue moisturizer + SPF 50+.
Days 5–7Recovery Peeling mostly complete. Resume light makeup. Avoid harsh actives until Day 7.
Days 7–25Between Sessions Strict sun protection. Resume normal skincare. Next session in 25 days.
06

Session plan

Sessions
4–6
Interval
25 days
Downtime
3–7 days
Total
4–5 months
Progressive dose schedule
SessionContact time
Session 110–15 min
Session 215–20 min
Session 320–25 min
Session 4+25–30 min (max)
07

Expected results

Clinical outcomes from supervised sessions. Actual results depend on skin type, adherence to protocol, and sun protection.

Case 01
Case 02
Case 03
Case 04